From a research point of view, placebos are often essential in determining the safety and efficacy of a treatment. On the other hand, research participants often hope they get active treatment, especially if it is for a disease they already have or might get.
Is it “fairto research participants to randomly assign them to receive either an active drug or an inactive substance? What about someone with a terminal illness, and the research drug is their last chance? What can be done to make the situation “more fair”?
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